The phrase “can legal weed win” can be interpreted in various ways, but assuming it refers to the legalization of cannabis, then this is dependent on political, societal, and legal landscapes which can change over time. In the United States, for instance, the trend has been toward the legalization or decriminalization of marijuana for both medicinal and recreational use in many states. Public opinion has shifted significantly over the past few decades, with a majority of Americans now supporting legalization. The “winning” of legal weed involves multifaceted factors including public opinion, advocacy, economic considerations, and political will. Various interest groups, including those from the health sector, criminal justice advocates, and businesses, can be instrumental in shaping the policy and legal environment regarding cannabis.